(See CONTRAINDICATIONS.). Storage: Store in a cool, dry place. Unlike chewable forms of flea prevention, Advantage® II is applied topically and kills flea eggs, flea larvae and adult fleas through contact with your treated dog. Advantage Multi™ for Cats (10% imidacloprid + 1% moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats. And by killing eggs and larvae, you can break the flea life cycle. At the discretion of the veterinarian, infected dogs should be treated with an adulticide to remove adult heartworms. The following clinical observations also occurred in laboratory effectiveness studies following application with Advantage Multi for Dogs and may be directly attributed to the drug or may be secondary to the intestinal parasite burden or other underlying conditions in the dogs: diarrhea, bloody stools, vomiting, anorexia, lethargy, coughing, ocular discharge and nasal discharge. Kills fleas through contact, so fleas don't have to bite your dog to die. Advantage spot-on flea treatment for cats contains an active ingredient that works fast, and is able to kill fleas through contact. Hypersensitivity reactions were not seen in the 5X treatment group. Dermal Dose Tolerance Study: Advantage Multi for Dogs was administered topically to 8-month-old Beagle dogs at 10X the recommended dose once. How Long Does Collagen Supplements Take to Work? First you need to set up an account with us, create a payment method, and send us your prescriptions. Advantage II for Cats kills fleas within 12 hours and reinfesting fleas within 2 hours. Yes. Place the tip of the tube on the skin and squeeze the tube to expel the entire contents directly on the skin, in one to four spots depending on your dog’s weight. Re-infesting or new fleas are killed within two hours for the remainder of the month. And with Advocate or Advantage-Multi it may be a “topical” but it goes thru the skin **to** the bloodstream to work. Use Advantage® II for dogs monthly, year-round to help keep your pet protected from fleas. Follow label directions for application. Turn the cap over and push the other end of cap onto the tip of the tube. Yes! Just make sure your dog is dry before application. Unlike chewable forms of flea prevention, Advantage® II is applied topically and kills flea eggs, flea larvae and adult fleas through contact with your treated dog. One puppy in the 1X treatment group had pruritus for one hour following the fifth treatment. Available for Android and iOS devices. To report a suspected adverse reaction, call 1-800-422-9874. If I were you, though, I would just wait until Monday and get Advantage II because Advantage Multi does NOT have the chemical that gets larvae and eggs, it has an alternative that gets heartworms and other worms, so you would be better off with Advantage II. If you choose to bathe your dog in between treatments, we recommend use of a general grooming shampoo for pets. Once-a-month topical solution for the prevention of heartworm disease, kills adult fleas, is indicated for the treatment of flea infestations, as well as the treatment and control of intestinal parasite infections in dogs and puppies that are at least 7 weeks of age and that weigh at least 3 lbs. If partly filled: Call your local solid waste agency for disposal instructions. Your dog should be standing for easy application. See product label for additional information. In avermectin sensitive dogs1, the signs may be Hold the applicator tube in an upright position facing away from you and your pet’s face and eyes. Separate treated dogs from one another and from other pets to reduce the risk of accidental ingestion. Prevents fleas on treated dogs from infesting your home, Prevents flea re-infestation by breaking the flea life cycle for 30 days, Treats, prevents and controls lice infestations. It doesn't take long for Advantage to go to work: In 12 hours at least 98 percent of the fleas on your dog will be dead. Bayer HealthCare LLC It kills fleas through contact, so fleas do not have to bite your dog to die. Owners reported the following signs in their dogs after application of Advantage Multifor Dogs: pruritus, flaky/greasy residue at the treatment site, medicinal odor, lethargy, inappetence, and hyperactivity. However, reinfestation from the emergence of pre-existing pupae in the environment may continue to occur for six weeks or longer … How long does it take for K9 Advantix® II to work on fleas? 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