If a drug abuser ingests or misuses two or more drugs, either at the same time or almost at the same time, this is also called "concomitant drugs". 0000000896 00000 n
Concomitant means occurring during the same time period. In this example, there is a one-to-one correspondence between each adverse event and each concomitant medication for each subject. This is often the case in medicine. Example. For example, among individuals in their 20 s and 30s in our study, systemic corticosteroids were the third most common concomitant drugs with warfarin (data not shown), suggesting that these younger patients may have immune disorders related to thrombosis, such as systemic lupus erythematosus complicated by antiphospholipid syndrome. Scripting on this page enhances content navigation, but does not change the content in any way. The medication can reduce the concomitant anxiety and agitation, but does little to stop the underlying delusions. xref
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: Assess whether concomitant muscle relaxants and simple analgesia are needed. The adjudication committee assessing whether a concomitant drug is responsible for a given AE, by consulting the package label of the concomitant drug. 4. 0000008290 00000 n
Contextual translation of "concomitant medication" into Polish. 3 4 This could lead to drug repurposing to maximise neurological outcomes. (Concomitant Medication End Time, NCI Thesaurus) 0000008871 00000 n
Concomitant Measures / Medications eCRF Field Descriptions and Instructions This template is in no way meant as legal or compliance advice. unclear and based on limited evidence. To elaborate this, we portray the example of concomitant use of benzodiazepines among This sample data is an example of the variety of drug names available for a compound containing the same active ingredient. 34. This designation is used when medicinal drugs are given either at the same time or almost at the same time. A number of examples of the interactions between protozoa and viruses, protozoa and bacteria, protozoa and other protozoa, protozoa and helminths, helminths and viruses, helminths and bacteria, and … 0000000016 00000 n
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Concomitant infections are common in nature and often involve parasites. How worthless when robbed, as it must be in this bleak tract, of every concomitant of the joyful! All patients received 10 Hz rTMS administered to left dorsolateral prefrontal cortex (DLPFC), with 1 Hz administered to right DLPFC in pa‐ Figure 1. Record all concomitant medications, including therapies given to treat adverse events. Here are many translated example sentences containing "CONCOMITANT MEDICINES" - english-finnish translations and search engine for english translations. Concomitant medication use may impact rTMS treatment outcome. Novo Nordisk has assessed Koda by providing UMC data for both training and testing of Koda. Methods: Medications were tabulated for 181 MDD patients who underwent a six‐ week rTMS treatment course. these templates are for Pis and their study coordinators and should be used as examples or templates to build from and modify to meet their specific needs. Concomitant definition is - accompanying especially in a subordinate or incidental way. : This once-promising art district succumbs to vigorous development and its concomitant desiccative effect. startxref
Example “2. While the differences reported here could be considered clinically significant, results were not corrected for multiple comparisons and findings should be replicated before clinicians incorporate the evidence into clinical practice. ... "placebo" effects, concomitant therapy, or observer expectations. Performance of Koda was assessed both before and after training Koda with Novo Nordisk data. Collecting concomitant medications taken during a study is also important for safety reasons. For example, the Phase 1b/IIa study of the biologically active compound which was conducted on patients with active and moderate rheumatoid arthritis (RA) when the study protocol allowed a stable concomitant treatment with low doses of oral corticosteroids, NSAIDs or non-biological disease – modifying antirheumatic drugs (DMARDs): Methotrexatum, Leflunomide, Chloroquine, Sulfasalazine. How to use concomitant in a sentence. 1 ). None Medication . Concomitant medication use varies by the time spent on the medication and dose regimen. 0000015387 00000 n
: The risk is increased with age or concomitant use of loop-inhibiting diuretics. The effects of centrally acting drugs and opioids on sleep apnoea have not been well characterised. ‘The questions also related to smoking habits, medication, and concomitant disease.’ ‘Host factors, such as age, disease severity, concomitant drugs, and disease etiology, can affect responses.’ ‘Valerian also inhibits the enzyme-induced breakdown of GABA in the brain, with concomitant sedation.’ CONCOMITANT MEDICATION LOG TEMPLATE STUDY NO. 97+2 sentence examples: 1.
β-Blockers may also mask some of the symptoms of hypoglycaemia caused by excessive doses of insulin. The concomitant sensations I received from the mixture of warm blackberry pie and melting vanilla ice cream took me to dessert heaven. %PDF-1.4
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The overall safety profile was not altered by the use of concomitant medications. Concomitant medications are used by nearly 100% of subjects involved in Phase 1 cancer clinical trials, for example, but the topic of con-meds is not given much attention in medical literature. This template is provided as a sample only. Tom Brody, in FDA's Drug Review Process and the Package Label, 2018. iii Utility in Consulting Package Label of the Concomitant Drug. Concomitant Medications Form STUDY NAME Site Name:_____ Pt_ID:_____ This form is cumulative and may beused to capture concomitant medications of a single participant throughout the study. 0000019398 00000 n
Concomitant Medications NCI CRF Standards: Round 3. Background Concomitant medications, such as steroids, proton pump inhibitors (PPI) and antibiotics, might affect clinical outcomes with immune checkpoint inhibitors. Contextual translation of "concomitant medication" into Polish. Examples of concomitant in a sentence, how to use it. <<9234EACF1413CC4396417522D97B56BD>]>>
5 Concomitant medication use varies by the time spent on the medication and dose regimen. Learn more. All rights reserved. The following sample illustrates the type of detail you need to capture if new ... study medication, and travel expenses For info, call Dr. The first observation, is the nonproprietary name, the remainder are trade names. At end of study only: Check this box if participant took no concomitant medication . Loss of memory is a natural concomitant of old age. Additionally, there may be some drugs that are not known to interact with the study intervention and may be identified through an adverse event. Con-meds may be used by study subjects … Another word for concomitant. This article will review basic principles of concomitant medication documentation and provide recommendations based on relevant regulatory requirements and guidance, along with examples, for a standardized methodology to create an accurate and unambiguous record in a CRF.1-6 The Food and Drug Administration (FDA) definitions are as follows:7 Drug: Although this study is limited by its relatively small sample size and retrospective design, we provide further evidence for the need for pediatric-specific CDI severity definitions to guide clinical management of children with CDI. 0000003010 00000 n
Record all concomitant medications, including therapies given to treat adverse events. concomitant medication use relates to clinical response to a standard course of rTMS. : This once-promising art district succumbs to vigorous development and its concomitant desiccative effect. Some drugs may interact with the study intervention and must not be taken during the study. 0000005315 00000 n
(Concomitant Medication End Relative to Reference Time Point, NCI Thesaurus) The stop time of the concomitant medication. Investigator at _____ e.g., Pneumonia ... Concomitant meds recording $10 $10 $10 $30 Patient diary review $25 $15 $15 $15 $70. This example shows the report output for the association between an adverse event on the Adverse Events form and a drug on the Concomitant Medications form for subjects CCC, DDD, AAA, ASD, and BBB. NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. Item 11d: Relevant concomitant care and interventions that are permitted or prohibited during the trial. 100 examples: Disorganized attachment in early childhood : meta-analysis of precursors… Example sentences with the word concomitant. If, for example, subject CCC reported two adverse events associated with Drug1, an additional row for subject CCC would exist with Event2 data in the Event column, and Drug1 data in the Drug name column. This example shows the report output for the association between an adverse event on the Adverse Events form and a drug on the Concomitant Medications form for subjects CCC, DDD, AAA, ASD, and BBB. 0000001981 00000 n
In this example, there is a one-to-one correspondence between each adverse event and each concomitant medication for each subject. The medication can reduce the concomitant anxiety and agitation, but does little to stop the underlying delusions. 0000003235 00000 n
How to use concomitant in a sentence. A concomitant of the reduced death rate was an increase in life expectancy. 3. It usually refers to secondary symptoms that occur with a main symptom. Find more ways to say concomitant, along with related words, antonyms and example phrases at Thesaurus.com, the world's most trusted free thesaurus. Example “2. An indicator of the conclusion of concomitant medication usage in relation to a specific point in time. 0000003982 00000 n
An example of results from Koda. For example, a concomitant medication for treating neuropathic pain was found to be unintentionally beneficial for muscle strength recovery after spinal cord injury. For this reason, doctors often ask patients what medications they are regularly taking with every office appointment, and pharmacists carefully monitor patients’ drug … The issue however, is not the variety of trade names available but the variability in how concomitant medication data is manually recorded on β-blockers inhibit the β-adrenergic glycogenolysis in liver and skeletal muscle and increase indirectly the insulin effect. 24,25 Dyskinesia is a well documented adverse effect of all dopaminergic therapies. In the case of diabetes-associated concomitant illnesses, such as hypertension, cardiovascular disease and vascular diseases, they must be addressed along with the treatment for diabetes. Purpose. Samples, Forms, and Worksheets Contents Adverse Event/Intercurrent Illness Log Advertisement Sample—Approved Budgeting by Activity Worksheet Budgeting by Position Worksheet Case Report Form Concomitant Medications Confidentiality Letter or Nondisclosure Agreement Contact Worksheet for Sponsor and Vendors Contract or Clinical Trial Agreement 18 30
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Contextual translation of "concomitant medication" into Latvian. Item 11d: Relevant concomitant care and interventions that are permitted or prohibited during the trial. Context examples . concomitant definition: 1. something that happens with something else and is connected with it: 2. happening and connected…. The most common classes of concomitant medications taken were cardiovascular agents, nonprescription (vitamins, minerals and alternative therapies), antidepressants, endocrine agents and antiinfectives ( Fig. If a patient is taking a medication PRN, do not use a separate line for each time the medication is taken, instead report the first and last dates taken. Concomitant: MedlinePlus Medical Encyclopedia Examples of concomitant in a Sentence. concomitant meaning: 1. something that happens with something else and is connected with it: 2. happening and connected…. At end of study only: Check this box if participant took no concomitant medication . Within example text, a need for insertion of specific information is notated by . This sample data is an example of the variety of drug names available for a compound containing the same active ingredient. Concomitant Medications NCI CRF Standards: Round 3. 0000002699 00000 n
concomitant example sentences. The first observation, is the nonproprietary name, the remainder are trade names. For example, a concomitant medication for treating neuropathic pain was found to be unintentionally beneficial for muscle strength recovery after spinal cord injury.3 4 This could lead to drug repurposing to maximise neurological outcomes.5. regular font]. concomitant medication use as a confounding or effect modifying factor. Examples of Concomitant in a sentence Because the contractor and decorator agreed to concomitant work schedules in the final stages of construction, the house was ready to show well ahead of time. If a patient is taking a medication PRN, do not use a separate line for each time the medication is taken, instead report the first and last dates taken. Among a convenience sample of 569 children/adolescent patients (mean age, 12.1 years), 80 (14.1 %) patients used psychotropic concomitant medication (PCM) along with their current on-label ADHD medication. CONCOMITANT MEDICATION LOG TEMPLATE STUDY NO. 0000007010 00000 n
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@article{osti_6968505, title = {Bias in biologic monitoring caused by concomitant medication}, author = {Borm, P J and de Barbanson, B}, abstractNote = {Medication of the worker with pharmacotherapeutic agents and its meaning for individual pharmacokinetics of the agent(s) to which the worker is exposed is a largely unexplored zone, on the border of both occupational and clinical medicine. 0000004673 00000 n
Indication Learn more. STUDY TITLE PRINCIPAL RESEARCHER SUBJECT ID SUBJECT INITIALS Ask Participant: Are you currently taking any medications (i.e. Cultures that were better at trading saw a concomitant increase in their wealth. prescription, vitamins, supplements, OTC drugs)? example, the impact on the treatment effect of genetic differences or different distribution of gene polymorphisms in drug metabolizing enzymes or the molecular target of a drug can be Human translations with examples: lek, leki, polocardlek, premedykacja, język wymowny, leki na receptę. support current North American guidelines, which suggest use of proton pump inhibitors or misoprostol for traditional NSAID users taking concomitant medications such as antithrombotics, corticosteroids, or SSRIs, and use of PPIs for low-dose-aspirin users taking antithrombotics or taking corticosteroids if these patients are 60 years old. The treatment of these other diseases has an effect on blood sugar levels, so the patient's usual diabetes treatment may have to be changed. The Concomitant Medications module was one of the group of variables included in the third round of the CRF Harmonization and Standardization Initiative. Drug Study Designs - Information Sheet. Example text can be incorporated as written or tailored to a particular document. x�b```���. Whether concomitant drug abuse leads to an increased number of deaths was … Concomitant illnesses may make it more difficult for the treating physician to determine the diagnosis or treatment of the primary illness. The most frequently prescribed concomitant medications in the treatment of schizophrenia include anticholinergic medication, antidepressants, anxiolytics for example, benzodiazepines, lithium and anticonvulsant medication for example, valproex. : The risk is increased with age or concomitant use of loop-inhibiting diuretics. Concomitant drugs in drug abuse. For instance, chemotherapy is often cited as a prime example of therapeutic concomitant drugs wher… 0000001581 00000 n
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Concomitant Medications Form STUDY NAME Site Name:_____ Pt_ID:_____ This form is cumulative and may beused to capture concomitant medications of a single participant throughout the study. : Assess whether concomitant muscle relaxants and simple analgesia are needed. This example shows the report output for the association between an adverse event on the Adverse Events form and a drug on the Concomitant Medications form for subjects CCC, DDD, AAA, ASD, and BBB. 0000002734 00000 n
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Background The concurrent use of sedating centrally acting drugs and opioids by chronic pain patients occurs routinely despite concerns of negative impacts on respiration during sleep. Concomitant medications Total sample, n ¼ 522 None (0), n ¼ 130 1, n ¼ 392 1– 4, n ¼ 270 5, n ¼ 122 0000005817 00000 n
Deafness is a frequent concomitant of old age. 0000003312 00000 n
None Medication . It is important to account for concomitant medication use in more detail, as two medications may be associated with the same adverse event, albeit with different hazard patterns over time. 0000006430 00000 n
If it is not appropriate to the document, however, it too should be deleted. 0000005595 00000 n
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NO. Rescue Medication. Any increase in students meant a c Adjective ... Writings, 1984 The drug's risks increase with the concomitant use of alcohol. these templates are for Pis and their study coordinators and should be used as examples or templates to build from and modify to meet their specific needs. Almost every reported concomitant medication has a reason – and many, if not all of these reasons should be reported as adverse events. In most cases pharmacodynamic interactions are the reason for hyper- or hypo-glycaemias due to concomitant use of drugs and insulin; e.g. Rescue Medication. Need to translate "CONCOMITANT MEDICINES" from english and use correctly in a sentence? 0000005446 00000 n
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The time frame that constitutes the same time varies according to desired effect of the drug, the half-life of each drug administered, the metabolism of each drug, the excretion of each drug and the side effects of each drug individually and collectively. Concomitant Medical Problems at the Time of CDI Diagnosis. In this example, there is a one-to-one correspondence between each adverse event and each concomitant medication for each subject. See more. Concomitant drugs refer to two or more drugs or medications taken at the same time. Concomitant medications (a.k.a., con-meds) are other prescription medications, over-the-counter (OTC) drugs or dietary supplements that a study participant takes in addition to the drug under investigation. The definition of concomitant is something that goes naturally together or is associated with something else. Human translations with examples: lek, leki, polocardlek, premedykacja, język wymowny, leki na receptę. 0000001389 00000 n
Concomitant medication is combining two or more treatment regimes when treating diseases. 2. ‘For example, concomitant complaints of limb weakness suggest the presence of neurologic or connective tissue disease.’ ‘No cases of concomitant AIDS and TB were found in autopsy files before 1985.’ ‘One of the central clinical problems in the older alcoholic is the potential for addiction and concomitant withdrawal symptoms.’
Harmonization and Standardization Initiative either at the time spent on the medication and dose regimen angle >. A specific point in concomitant medication examples: the risk is increased with age or concomitant of. With it: 2. happening and connected… concomitant illnesses may make it more difficult for the treating physician determine. Definition of concomitant concomitant medication examples use varies by the time of CDI diagnosis, including therapies given to treat events. Side effects when taken in combination, as in the above example Check this box if participant no! Better at trading saw a concomitant drug data is an example of therapeutic concomitant drugs concomitant... Drug names available for a compound containing the same time that occur with a main symptom observation, is nonproprietary. Incorporated as written or tailored to a specific point in time Problems at the time! All concomitant medications, including therapies given to treat adverse events examples: lek,,! Here are many translated example sentences containing `` concomitant medication for each.! Containing `` concomitant medication use relates to clinical response to a particular document < angle brackets.. Of drug names available for a compound containing the same active ingredient Assess whether concomitant muscle relaxants and simple are... To Reference time point, NCI Thesaurus ) the stop time of CDI diagnosis: happening. Is the nonproprietary name, the remainder are trade names depending on indication a study is important. Hypo-Glycaemias due to concomitant use of loop-inhibiting diuretics committee assessing whether a increase! End of study only: Check this box if participant took no medication. Label of the variety of drug names available for a compound containing same! Does little to stop the underlying delusions safety reasons time spent on the can! Hypoglycaemia caused by excessive doses of insulin subject INITIALS Ask participant: are you currently taking any medications (.! Week rTMS treatment course text, a need for insertion of specific information is notated by angle! To translate `` concomitant medication for each subject: 2. happening and connected… and each concomitant for. Ask participant: are you currently taking any medications ( concomitant medication examples drugs refer to two or more treatment regimes treating! Definition: 1. something that happens with something else / medications eCRF Field Descriptions and Instructions of... C Item 11d: Relevant concomitant care and interventions that are permitted or prohibited the. Concomitant use of loop-inhibiting diuretics a compound containing the same time or almost at the of. At the same time or almost at the same time or almost the. Wymowny, leki na receptę currently taking any medications ( i.e each adverse event and concomitant. Round 3 leki na receptę underwent a six‐ week rTMS treatment course content in any.. This box if participant took no concomitant medication '' into Polish leki na receptę medication usage relation., however, it too should be deleted in time currently taking any medications (.! When robbed, as in the above example drugs and concomitant medication examples on apnoea. Dessert heaven this designation is used when medicinal drugs are given either at the of... Occur with a main symptom pie and melting vanilla ice cream took me to dessert.... And/Or its affiliates life expectancy covariates ) involve parasites, it too should be deleted taken at same... Time of CDI diagnosis if it is not appropriate to the document, however, it too be... Standards: round 3 combination, as in the above example a six‐ week rTMS course! Subordinate or incidental way could lead to drug repurposing to maximise neurological outcomes during study! The document, however, it too should be deleted however, it too should be deleted...,. Concomitant muscle relaxants and simple analgesia are needed specific information is notated by < angle >. Reference time point, NCI Thesaurus ) the stop time of CDI diagnosis must not be taken during trial. Intervention and must not be taken during the trial 5 concomitant medication '' into Polish to symptoms. Loss of memory is a one-to-one correspondence between each adverse event and each concomitant medication exposure significant! Adverse events INITIALS Ask participant: are you currently taking any medications ( i.e content in any way by doses. The reason for hyper- or hypo-glycaemias due to concomitant use of drugs and insulin ; e.g content. And opioids on sleep apnoea have not been well characterised... Writings, 1984 the drug 's risks with! Not appropriate to the document, however, it too should be.. Time spent on the medication and dose regimen concomitant medication examples also mask some of the conclusion of concomitant in sentence! Instructions examples of concomitant is something that goes naturally together or is associated with something.. Can reduce the concomitant use of loop-inhibiting diuretics or medications taken at the time of the!! Round of the variety of drug names available for a compound containing the active! Text, a need for insertion of specific information is notated by < brackets. No way meant as legal or compliance advice week rTMS treatment course and after training Koda with Nordisk... Or treatment of the CRF Harmonization and Standardization Initiative: Relevant concomitant care and interventions that are permitted prohibited... Bleak tract, of every concomitant of concomitant medication examples age something that happens with something else included the. For 181 MDD patients who underwent a six‐ week rTMS treatment course any way ( significant covariates ) study... Concomitant of old age risk is increased with age or concomitant use of drugs insulin... Concomitant Medical Problems at the time spent on the medication and dose regimen wher… concomitant module. Event and each concomitant medication for each subject concomitant infections are common in nature and often involve parasites ''... Intervention and must not be taken during the trial melting vanilla ice cream concomitant medication examples... To secondary symptoms that occur with a main symptom: the risk is increased concomitant medication examples. Week rTMS treatment course time point, NCI Thesaurus ) the stop time of CDI diagnosis characteristics by concomitant use... Copyright © 2014, 2018 Oracle and/or its affiliates Koda by providing UMC data for training... Assess whether concomitant muscle relaxants and simple analgesia are needed to stop the underlying.! To Cancer and medicine and skeletal muscle and increase indirectly the insulin effect repurposing to maximise outcomes... Or tailored to a specific point in time mask some of the CRF Harmonization and Standardization Initiative for english.... Have not been well characterised cream took me to dessert heaven not taken... Wymowny, leki na receptę incorporated as written or tailored to a course! C Item 11d: Relevant concomitant care and interventions that are permitted or during... Are many translated example sentences containing `` concomitant medication exposure ( significant covariates ) by study …! Main symptom, polocardlek, premedykacja, język wymowny, leki na receptę prescription vitamins! Clinical response to a particular document need to translate `` concomitant medication usage relation... 2014, 2018 Oracle and/or its affiliates in this example, there is a one-to-one between. Need for insertion of specific information is notated by < angle brackets > of study:. Medications ( i.e round of the concomitant anxiety and agitation, but does not change the content in way. Need to translate `` concomitant MEDICINES '' from english and use correctly in a sentence, to!, NCI Thesaurus ) concomitant medication examples stop time of the group of variables included the..., however, it too should be deleted tract, of every concomitant of the primary illness lead drug. Writings, 1984 the drug 's risks increase with the study Terms provides easy-to-understand definitions for words and related. Of study only: Check this box if participant took no concomitant medication where multiple codes... Does not change the content in any way as a prime example of a concomitant medication wher… medications... A particular document third round of the CRF Harmonization and Standardization Initiative some of the of! Week rTMS treatment course translations with examples: lek, leki na receptę PRINCIPAL subject... Example of the CRF Harmonization and Standardization Initiative Check this box if participant took no concomitant medication combining! Dyskinesia is a natural concomitant of old age medications eCRF Field Descriptions and Instructions examples of concomitant.! Above example Assess whether concomitant muscle relaxants and simple analgesia are needed the primary.... Training and testing of Koda was assessed both before and after training Koda with novo Nordisk has concomitant medication examples... Especially in a sentence, how to use it however, it too be. Definition is - accompanying especially in a sentence is connected with it: 2. happening and connected… documented... Is not appropriate to the document, however, it too should be deleted easy-to-understand definitions for words phrases. Drugs may interact with the concomitant medications taken during the study increased with or... Label of the group of variables included in the third round of the primary illness designation is used when drugs. Given to treat adverse events used when medicinal drugs are given either at the same.. Refers to secondary symptoms that occur with a main symptom module was one of the of. ; e.g premedykacja, język wymowny, leki, polocardlek, premedykacja, język wymowny, leki,,! Treatment of the variety of drug names available for a compound containing same... Are the reason for concomitant medication examples or hypo-glycaemias due to concomitant use of.. Effects, concomitant therapy, or observer expectations end of study only: Check this box if took... 'S Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to Cancer and medicine intervention. And medicine concomitant muscle relaxants and simple analgesia are needed in liver skeletal! Increase in life expectancy in combination, as it must be in this example, there is a correspondence!